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Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes

This study investigates the effects and possible mechanism of an agonist of PPARα, Wy14643, on primary hepatocytes subjected to H/R injury in rats. H/R induced a significant increase ALT, AST, MDA in the culture medium and ROS in the hepatocytes. These effects were reversed by pretreatment with Wy14...

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Detalles Bibliográficos
Autores principales:	Chen, Ke, Li, Yuan-Hai, Xu, Si-Qi, Hu, Sheng-Hong, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191773/ https://www.ncbi.nlm.nih.gov/pubmed/22007188 http://dx.doi.org/10.1155/2012/547980

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