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p53 Family: Role of Protein Isoforms in Human Cancer

TP53, TP63, and TP73 genes comprise the p53 family. Each gene produces protein isoforms through multiple mechanisms including extensive alternative mRNA splicing. Accumulating evidence shows that these isoforms play a critical role in the regulation of many biological processes in normal cells. Thei...

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Detalles Bibliográficos
Autores principales: Wei, Jinxiong, Zaika, Elena, Zaika, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191818/
https://www.ncbi.nlm.nih.gov/pubmed/22007292
http://dx.doi.org/10.1155/2012/687359