SUMOylation of the Forkhead Transcription Factor FOXL2 Promotes Its Stabilization/Activation through Transient Recruitment to PML Bodies

BACKGROUND: FOXL2 is a transcription factor essential for ovarian development and maintenance. It is mutated in the genetic condition called Blepharophimosis Ptosis Epicantus inversus Syndrome (BPES) and in cases of isolated premature ovarian failure. We and others have previously shown that FOXL2 u...

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Detalles Bibliográficos
Autores principales: Georges, Adrien, Benayoun, Bérénice A., Marongiu, Mara, Dipietromaria, Aurélie, L'Hôte, David, Todeschini, Anne-Laure, Auer, Jana, Crisponi, Laura, Veitia, Reiner A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192040/
https://www.ncbi.nlm.nih.gov/pubmed/22022399
http://dx.doi.org/10.1371/journal.pone.0025463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192040/
https://www.ncbi.nlm.nih.gov/pubmed/22022399
http://dx.doi.org/10.1371/journal.pone.0025463

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