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Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity
The NF-κB pathway is regulated by multiple post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. Many of these modifications act on the natural inhibitor IκBα modulating its capacity to control signal-mediated NF-κB activity. While the canonical pathway involvin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192046/ https://www.ncbi.nlm.nih.gov/pubmed/22022389 http://dx.doi.org/10.1371/journal.pone.0025397 |