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Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9

BACKGROUND: M-phase phosphoprotein 8 (MPP8) was initially identified to be a component of the RanBPM-containing large protein complex, and has recently been shown to bind to methylated H3K9 both in vivo and in vitro. MPP8 binding to methylated H3K9 is suggested to recruit the H3K9 methyltransferases...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Zhihong, Ruan, Jianbin, Xu, Chao, Tong, Yufeng, Pan, Patricia W., Tempel, Wolfram, Crombet, Lissete, Min, Jinrong, Zang, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192050/
https://www.ncbi.nlm.nih.gov/pubmed/22022377
http://dx.doi.org/10.1371/journal.pone.0025104