Cargando…
Spreading of Alu Methylation to the Promoter of the MLH1 Gene in Gastrointestinal Cancer
The highly repetitive Alu retroelements are regarded as methylation centres in the genome. Methylation in the gene promoters could be spreading from them. Promoter methylation of MLH1 is frequently detected in cancers, but the underlying mechanism is unclear. The aim of this study is to understand w...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192117/ https://www.ncbi.nlm.nih.gov/pubmed/22022465 http://dx.doi.org/10.1371/journal.pone.0025913 |