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Impact of the RTS,S Malaria Vaccine Candidate on Naturally Acquired Antibody Responses to Multiple Asexual Blood Stage Antigens

BACKGROUND: Partial protective efficacy lasting up to 43 months after vaccination with the RTS,S malaria vaccine has been reported in one cohort (C1) of a Phase IIb trial in Mozambique, but waning efficacy was observed in a smaller contemporaneous cohort (C2). We hypothesized that low dose exposure...

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Detalles Bibliográficos
Autores principales: Campo, Joseph J., Dobaño, Carlota, Sacarlal, Jahit, Guinovart, Caterina, Mayor, Alfredo, Angov, Evelina, Dutta, Sheetij, Chitnis, Chetan, Macete, Eusebio, Aponte, John J., Alonso, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192128/
https://www.ncbi.nlm.nih.gov/pubmed/22022448
http://dx.doi.org/10.1371/journal.pone.0025779