Suv4-20h Abrogation Enhances Telomere Elongation during Reprogramming and Confers a Higher Tumorigenic Potential to iPS Cells

Reprogramming of adult differentiated cells to induced pluripotent stem cells (iPS) cells has been achieved by over-expression of specific transcription factors. Nuclear reprogramming induces a series of profound changes at the telomeres of the parental differentiated cells, including a telomerase-d...

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Detalles Bibliográficos
Autores principales: Marión, Rosa M., Schotta, Gunnar, Ortega, Sagrario, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192133/
https://www.ncbi.nlm.nih.gov/pubmed/22022429
http://dx.doi.org/10.1371/journal.pone.0025680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192133/
https://www.ncbi.nlm.nih.gov/pubmed/22022429
http://dx.doi.org/10.1371/journal.pone.0025680

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