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The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway
The retinoblastoma tumor suppressor (pRb) regulates cell cycle entry, progression and exit by controlling the activity of the E2F-family of transcription factors. During cell cycle exit pRb acts as a transcriptional repressor by associating with E2F proteins and thereby inhibiting their ability to s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192141/ https://www.ncbi.nlm.nih.gov/pubmed/22022495 http://dx.doi.org/10.1371/journal.pone.0026019 |