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The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway

The retinoblastoma tumor suppressor (pRb) regulates cell cycle entry, progression and exit by controlling the activity of the E2F-family of transcription factors. During cell cycle exit pRb acts as a transcriptional repressor by associating with E2F proteins and thereby inhibiting their ability to s...

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Detalles Bibliográficos
Autores principales: Sáenz Robles, Maria Teresa, Case, Ashley, Chong, Jean-Leon, Leone, Gustavo, Pipas, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192141/
https://www.ncbi.nlm.nih.gov/pubmed/22022495
http://dx.doi.org/10.1371/journal.pone.0026019