Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. In addition to cognitive deficits, FXS patients exhibit hyperactivity, attention deficits, social difficulties, anxiety, and other autistic-like behaviors. FXS is caused by an expanded CGG trinucleotide repeat in...

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Detalles Bibliográficos
Autores principales: Sheridan, Steven D., Theriault, Kraig M., Reis, Surya A., Zhou, Fen, Madison, Jon M., Daheron, Laurence, Loring, Jeanne F., Haggarty, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192166/
https://www.ncbi.nlm.nih.gov/pubmed/22022567
http://dx.doi.org/10.1371/journal.pone.0026203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192166/
https://www.ncbi.nlm.nih.gov/pubmed/22022567
http://dx.doi.org/10.1371/journal.pone.0026203

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