Cargando…

A human memory T-cell subset with stem cell-like properties

Immunological memory is thought to depend upon a stem cell-like, self-renewing population of lymphocytes capable of differentiating into effector cells in response to antigen re-exposure. Here we describe a long-lived human memory T-cell population that displays enhanced self-renewal and multipotent...

Descripción completa

Detalles Bibliográficos
Autores principales: Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M., Quigley, Máire F., Almeida, Jorge R., Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C., Price, David A., June, Carl H., Marincola, Francesco M., Roederer, Mario, Restifo, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192229/
https://www.ncbi.nlm.nih.gov/pubmed/21926977
http://dx.doi.org/10.1038/nm.2446