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A human memory T-cell subset with stem cell-like properties
Immunological memory is thought to depend upon a stem cell-like, self-renewing population of lymphocytes capable of differentiating into effector cells in response to antigen re-exposure. Here we describe a long-lived human memory T-cell population that displays enhanced self-renewal and multipotent...
Autores principales: | Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M., Quigley, Máire F., Almeida, Jorge R., Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C., Price, David A., June, Carl H., Marincola, Francesco M., Roederer, Mario, Restifo, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192229/ https://www.ncbi.nlm.nih.gov/pubmed/21926977 http://dx.doi.org/10.1038/nm.2446 |
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