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Glutamate Release by Primary Brain Tumors Induces Epileptic Activity

Epileptic seizures are a common and poorly understood co-morbidity for individuals with primary brain tumors. To investigate peritumoral seizure etiology, we implanted patient-derived glioma cells into scid mice. Within 14–18 days, glioma-bearing animals developed spontaneous, recurring abnormal EEG...

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Detalles Bibliográficos
Autores principales: Buckingham, Susan C., Campbell, Susan L., Haas, Brian R., Montana, Vedrana, Robel, Stefanie, Ogunrinu, Toyin, Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192231/
https://www.ncbi.nlm.nih.gov/pubmed/21909104
http://dx.doi.org/10.1038/nm.2453