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Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria

Using the mitochondrial potential (ΔΨ(m)) marker JC-1 (5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide) and high-resolution imaging, we functionally analyzed mitochondria in cultured rat hippocampal astrocytes. Ratiometric detection of JC-1 fluorescence identified mitocho...

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Detalles Bibliográficos
Autores principales: Keil, Vera C., Funke, Frank, Zeug, Andre, Schild, Detlev, Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192276/
https://www.ncbi.nlm.nih.gov/pubmed/21881871
http://dx.doi.org/10.1007/s00424-011-1012-8