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Case-Control Study of Vitamin D, dickkopf homolog 1 (DKK1) Gene Methylation, VDR Gene Polymorphism and the Risk of Colon Adenoma in African Americans

BACKGROUND: There are sparse data on genetic, epigenetic and vitamin D exposure in African Americans (AA) with colon polyp. Consequently, we evaluated serum 25(OH) D levels, vitamin D receptor (VDR) polymorphisms and the methylation status of the tumor suppressor gene dickkopf homolog 1 (DKK1) as ri...

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Detalles Bibliográficos
Autores principales: Ashktorab, Hassan, Nguza, Bijou, Fatemi, Mehrnaz, Nouraie, Mehdi, Smoot, Duane T., Schäffer, Alejandro A., Kupfer, Sonia S., Camargo, Carlos A., Brim, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192764/
https://www.ncbi.nlm.nih.gov/pubmed/22022386
http://dx.doi.org/10.1371/journal.pone.0025314