Association of TLR7 Variants with AIDS-Like Disease and AIDS Vaccine Efficacy in Rhesus Macaques

In HIV infection, TLR7-triggered IFN-α production exerts a direct antiviral effect through the inhibition of viral replication, but may also be involved in immune pathogenesis leading to AIDS. TLR7 could also be an important mediator of vaccine efficacy. In this study, we analyzed polymorphisms in t...

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Detalles Bibliográficos
Autores principales: Siddiqui, Roman A., Krawczak, Michael, Platzer, Matthias, Sauermann, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192768/
https://www.ncbi.nlm.nih.gov/pubmed/22022401
http://dx.doi.org/10.1371/journal.pone.0025474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192768/
https://www.ncbi.nlm.nih.gov/pubmed/22022401
http://dx.doi.org/10.1371/journal.pone.0025474

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