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Stretching Actin Filaments within Cells Enhances their Affinity for the Myosin II Motor Domain

To test the hypothesis that the myosin II motor domain (S1) preferentially binds to specific subsets of actin filaments in vivo, we expressed GFP-fused S1 with mutations that enhanced its affinity for actin in Dictyostelium cells. Consistent with the hypothesis, the GFP-S1 mutants were localized alo...

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Detalles Bibliográficos
Autores principales: Uyeda, Taro Q. P., Iwadate, Yoshiaki, Umeki, Nobuhisa, Nagasaki, Akira, Yumura, Shigehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192770/
https://www.ncbi.nlm.nih.gov/pubmed/22022566
http://dx.doi.org/10.1371/journal.pone.0026200