Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease

BACKGROUND: Previously we demonstrated that DNA vaccination of nonhuman primates (NHP) with a small subset of vaccinia virus (VACV) immunogens (L1, A27, A33, B5) protects against lethal monkeypox virus challenge. The L1 and A27 components of this vaccine target the mature virion (MV) whereas A33 and...

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Detalles Bibliográficos
Autores principales: Golden, Joseph W, Zaitseva, Marina, Kapnick, Senta, Fisher, Robert W, Mikolajczyk, Malgorzata G, Ballantyne, John, Golding, Hana, Hooper, Jay W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192780/
https://www.ncbi.nlm.nih.gov/pubmed/21933385
http://dx.doi.org/10.1186/1743-422X-8-441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192780/
https://www.ncbi.nlm.nih.gov/pubmed/21933385
http://dx.doi.org/10.1186/1743-422X-8-441

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