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Barriers to Diffusion in Dendrites and Estimation of Calcium Spread Following Synaptic Inputs

The motion of ions, molecules or proteins in dendrites is restricted by cytoplasmic obstacles such as organelles, microtubules and actin network. To account for molecular crowding, we study the effect of diffusion barriers on local calcium spread in a dendrite. We first present a model based on a di...

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Detalles Bibliográficos
Autores principales: Biess, Armin, Korkotian, Eduard, Holcman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192802/
https://www.ncbi.nlm.nih.gov/pubmed/22022241
http://dx.doi.org/10.1371/journal.pcbi.1002182