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Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing
Messenger RNA splicing is an essential and complex process for the removal of intron sequences. Whereas the composition of the splicing machinery is mostly known, the kinetics of splicing, the catalytic activity of splicing factors and the interdependency of transcription, splicing and mRNA 3′ end f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192812/ https://www.ncbi.nlm.nih.gov/pubmed/22022255 http://dx.doi.org/10.1371/journal.pcbi.1002215 |