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Preventing Dangerous Nonsense: Selection for Robustness to Transcriptional Error in Human Genes
Nonsense Mediated Decay (NMD) degrades transcripts that contain a premature STOP codon resulting from mistranscription or missplicing. However NMD's surveillance of gene expression varies in efficiency both among and within human genes. Previous work has shown that the intron content of human g...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192821/ https://www.ncbi.nlm.nih.gov/pubmed/22022272 http://dx.doi.org/10.1371/journal.pgen.1002276 |