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Number and Size Distribution of Colorectal Adenomas under the Multistage Clonal Expansion Model of Cancer

Colorectal cancer (CRC) is believed to arise from mutant stem cells in colonic crypts that undergo a well-characterized progression involving benign adenoma, the precursor to invasive carcinoma. Although a number of (epi)genetic events have been identified as drivers of this process, little is known...

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Detalles Bibliográficos
Autores principales: Dewanji, Anup, Jeon, Jihyoun, Meza, Rafael, Luebeck, E. Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192823/
https://www.ncbi.nlm.nih.gov/pubmed/22022253
http://dx.doi.org/10.1371/journal.pcbi.1002213