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Number and Size Distribution of Colorectal Adenomas under the Multistage Clonal Expansion Model of Cancer
Colorectal cancer (CRC) is believed to arise from mutant stem cells in colonic crypts that undergo a well-characterized progression involving benign adenoma, the precursor to invasive carcinoma. Although a number of (epi)genetic events have been identified as drivers of this process, little is known...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192823/ https://www.ncbi.nlm.nih.gov/pubmed/22022253 http://dx.doi.org/10.1371/journal.pcbi.1002213 |