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A Phenomics-Based Strategy Identifies Loci on APOC1, BRAP, and PLCG1 Associated with Metabolic Syndrome Phenotype Domains

Despite evidence of the clustering of metabolic syndrome components, current approaches for identifying unifying genetic mechanisms typically evaluate clinical categories that do not provide adequate etiological information. Here, we used data from 19,486 European American and 6,287 African American...

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Detalles Bibliográficos
Autores principales: Avery, Christy L., He, Qianchuan, North, Kari E., Ambite, Jose L., Boerwinkle, Eric, Fornage, Myriam, Hindorff, Lucia A., Kooperberg, Charles, Meigs, James B., Pankow, James S., Pendergrass, Sarah A., Psaty, Bruce M., Ritchie, Marylyn D., Rotter, Jerome I., Taylor, Kent D., Wilkens, Lynne R., Heiss, Gerardo, Lin, Dan Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192835/
https://www.ncbi.nlm.nih.gov/pubmed/22022282
http://dx.doi.org/10.1371/journal.pgen.1002322