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A Phenomics-Based Strategy Identifies Loci on APOC1, BRAP, and PLCG1 Associated with Metabolic Syndrome Phenotype Domains
Despite evidence of the clustering of metabolic syndrome components, current approaches for identifying unifying genetic mechanisms typically evaluate clinical categories that do not provide adequate etiological information. Here, we used data from 19,486 European American and 6,287 African American...
Autores principales: | Avery, Christy L., He, Qianchuan, North, Kari E., Ambite, Jose L., Boerwinkle, Eric, Fornage, Myriam, Hindorff, Lucia A., Kooperberg, Charles, Meigs, James B., Pankow, James S., Pendergrass, Sarah A., Psaty, Bruce M., Ritchie, Marylyn D., Rotter, Jerome I., Taylor, Kent D., Wilkens, Lynne R., Heiss, Gerardo, Lin, Dan Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192835/ https://www.ncbi.nlm.nih.gov/pubmed/22022282 http://dx.doi.org/10.1371/journal.pgen.1002322 |
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