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KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection

Killer cell immunoglobulin-like receptors (KIRs) influence both innate and adaptive immunity. But while the role of KIRs in NK-mediated innate immunity is well-documented, the impact of KIRs on the T cell response in human disease is not known. Here we test the hypothesis that an individual's K...

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Detalles Bibliográficos
Autores principales: Seich al Basatena, Nafisa-Katrin, MacNamara, Aidan, Vine, Alison M., Thio, Chloe L., Astemborski, Jacquie, Usuku, Koichiro, Osame, Mitsuhiro, Kirk, Gregory D., Donfield, Sharyne M., Goedert, James J., Bangham, Charles R.M., Carrington, Mary, Khakoo, Salim I., Asquith, Becca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192839/
https://www.ncbi.nlm.nih.gov/pubmed/22022261
http://dx.doi.org/10.1371/journal.ppat.1002270