Mitochondrial Ccs1 contains a structural disulfide bond crucial for the import of this unconventional substrate by the disulfide relay system

The copper chaperone for superoxide dismutase 1 (Ccs1) provides an important cellular function against oxidative stress. Ccs1 is present in the cytosol and in the intermembrane space (IMS) of mitochondria. Its import into the IMS depends on the Mia40/Erv1 disulfide relay system, although Ccs1 is, in...

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Detalles Bibliográficos
Autores principales: Groß, Dominik P., Burgard, Caroline A., Reddehase, Silvia, Leitch, Jeffry M., Culotta, Valeria C., Hell, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192856/
https://www.ncbi.nlm.nih.gov/pubmed/21865601
http://dx.doi.org/10.1091/mbc.E11-04-0296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192856/
https://www.ncbi.nlm.nih.gov/pubmed/21865601
http://dx.doi.org/10.1091/mbc.E11-04-0296

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