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Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na(+)/H(+) exchanger NHE3 by glucocorticoids

Na(+)/H(+) exchanger 3 (NHE3) is the major Na(+) transporter in the intestine. Serum- and glucocorticoid-induced kinase (SGK) 1 interacts with NHE regulatory factor 2 (NHERF2) and mediates activation of NHE3 by dexamethasone (Dex) in cultured epithelial cells. In this study, we compared short-term r...

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Detalles Bibliográficos
Autores principales: He, Peijian, Lee, Sei-Jung, Lin, Songbai, Seidler, Ursula, Lang, Florian, Fejes-Toth, Geza, Naray-Fejes-Toth, Aniko, Yun, C. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192861/
https://www.ncbi.nlm.nih.gov/pubmed/21865597
http://dx.doi.org/10.1091/mbc.E11-04-0328