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ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility
Rho GTPases are molecular switches that transmit biochemical signals in response to extracellular stimuli to elicit changes in the actin cytoskeleton. Rho GTPases cycle between an active, GTP-bound state and an inactive, GDP-bound state. These states are regulated by two distinct families of protein...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192863/ https://www.ncbi.nlm.nih.gov/pubmed/21865595 http://dx.doi.org/10.1091/mbc.E11-04-0364 |