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MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

BACKGROUND: Perturbation of DNA methylation is frequent in cancers and has emerged as an important mechanism involved in tumorigenesis. To determine how DNA methylation is modified in the genome of primary glioma, we used Methyl-DNA immunoprecipitation (MeDIP) and Nimblegen CpG promoter microarrays...

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Detalles Bibliográficos
Autores principales: Zhang, Zuping, Tang, Hailin, Wang, Zeyou, Zhang, Baoxin, Liu, Wei, Lu, Hongmei, Xiao, Lan, Liu, Xiaoping, Wang, Rong, Li, Xiaoling, Wu, Minghua, Li, Guiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193026/
https://www.ncbi.nlm.nih.gov/pubmed/21962230
http://dx.doi.org/10.1186/1476-4598-10-124