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Changes of Pulmonary Pathology and Gene Expressions After Simvastatin Treatment in the Monocrotaline-Induced Pulmonary Hypertension Rat Model

BACKGROUND AND OBJECTIVES: Simvastatin's properties are suggestive of a potential pathophysiologic role in pulmonary hypertension. The objectives of this study were to investigate changes of pulmonary pathology and gene expressions, including endothelin (ET)-1, endothelin receptor A (ERA), indu...

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Detalles Bibliográficos
Autores principales: Lee, Yun Hee, Kim, Kwan Chang, Cho, Min-Sun, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Cardiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193043/
https://www.ncbi.nlm.nih.gov/pubmed/22022327
http://dx.doi.org/10.4070/kcj.2011.41.9.518