Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) and suppressed apoptosis. This phenotype has been associated with the upregulation of the oncoprotein survivin promoting mitochond...

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Detalles Bibliográficos
Autores principales: Courboulin, Audrey, Tremblay, Véronique L, Barrier, Marjorie, Meloche, Jolyane, Jacob, Maria Helena, Chapolard, Mathilde, Bisserier, Malik, Paulin, Roxane, Lambert, Caroline, Provencher, Steeve, Bonnet, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193170/
https://www.ncbi.nlm.nih.gov/pubmed/21951574
http://dx.doi.org/10.1186/1465-9921-12-128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193170/
https://www.ncbi.nlm.nih.gov/pubmed/21951574
http://dx.doi.org/10.1186/1465-9921-12-128

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