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dFOXO-independent effects of reduced insulin-like signaling in Drosophila

The insulin/insulin-like growth factor-like signaling (IIS) pathway in metazoans has evolutionarily conserved roles in growth control, metabolic homeostasis, stress responses, reproduction, and lifespan. Genetic manipulations that reduce IIS in the nematode worm Caenorhabditis elegans, the fruit fly...

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Detalles Bibliográficos
Autores principales: Slack, Cathy, Giannakou, Maria E, Foley, Andrea, Goss, Martin, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193374/
https://www.ncbi.nlm.nih.gov/pubmed/21443682
http://dx.doi.org/10.1111/j.1474-9726.2011.00707.x