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dFOXO-independent effects of reduced insulin-like signaling in Drosophila
The insulin/insulin-like growth factor-like signaling (IIS) pathway in metazoans has evolutionarily conserved roles in growth control, metabolic homeostasis, stress responses, reproduction, and lifespan. Genetic manipulations that reduce IIS in the nematode worm Caenorhabditis elegans, the fruit fly...
Autores principales: | Slack, Cathy, Giannakou, Maria E, Foley, Andrea, Goss, Martin, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193374/ https://www.ncbi.nlm.nih.gov/pubmed/21443682 http://dx.doi.org/10.1111/j.1474-9726.2011.00707.x |
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