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Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors. The low efficiency of reprogramming and genomic integration of oncogenes and viral vectors limited the potential application of iPSCs. Here we report that Lithium (Li), a drug used to treat mood disorde...

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Detalles Bibliográficos
Autores principales: Wang, Quan, Xu, Xinxiu, Li, Jun, Liu, Jing, Gu, Haifeng, Zhang, Ru, Chen, Jiekai, Kuang, Yin, Fei, Jian, Jiang, Cong, Wang, Ping, Pei, Duanqing, Ding, Sheng, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193456/
https://www.ncbi.nlm.nih.gov/pubmed/21727907
http://dx.doi.org/10.1038/cr.2011.108