Regulation of DNA Repair Mechanism in Human Glioma Xenograft Cells both In Vitro and In Vivo in Nude Mice

BACKGROUND: Glioblastoma Multiforme (GBM) is the most lethal form of brain tumor. Efficient DNA repair and anti-apoptotic mechanisms are making glioma treatment difficult. Proteases such as MMP9, cathepsin B and urokinase plasminogen activator receptor (uPAR) are over expressed in gliomas and contri...

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Detalles Bibliográficos
Autores principales: Ponnala, Shivani, Veeravalli, Krishna Kumar, Chetty, Chandramu, Dinh, Dzung H., Rao, Jasti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193530/
https://www.ncbi.nlm.nih.gov/pubmed/22022560
http://dx.doi.org/10.1371/journal.pone.0026191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193530/
https://www.ncbi.nlm.nih.gov/pubmed/22022560
http://dx.doi.org/10.1371/journal.pone.0026191

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