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Recruitment and Activation of Pancreatic Stellate Cells from the Bone Marrow in Pancreatic Cancer: A Model of Tumor-Host Interaction

BACKGROUND AND AIMS: Chronic pancreatitis and pancreatic cancer are characterised by extensive stellate cell mediated fibrosis, and current therapeutic development includes targeting pancreatic cancer stroma and tumor-host interactions. Recent evidence has suggested that circulating bone marrow deri...

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Detalles Bibliográficos
Autores principales: Scarlett, Christopher J., Colvin, Emily K., Pinese, Mark, Chang, David K., Morey, Adrienne L., Musgrove, Elizabeth A., Pajic, Marina, Apte, Minoti, Henshall, Susan M., Sutherland, Robert L., Kench, James G., Biankin, Andrew V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193536/
https://www.ncbi.nlm.nih.gov/pubmed/22022519
http://dx.doi.org/10.1371/journal.pone.0026088