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Inhibition of Transcription Factor Specificity Protein 1 Alters the Gene Expression Profile of Keratinocytes Leading to Up-regulation of Kallikrein-related Peptidases and TSLP

Transcription factor specificity protein 1 (Sp1) is involved in diverse cellular functions. We recently found that Sp1 was significantly decreased in skin biopsies from patients with atopic dermatitis (AD) and had an even greater reduction in AD patients with a history of eczema herpeticum. In the c...

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Detalles Bibliográficos
Autores principales: Bin, Lianghua, Kim, Byung Eui, Hall, Clifton F, Leach, Sonia M, Leung, Donald YM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193562/
https://www.ncbi.nlm.nih.gov/pubmed/21753780
http://dx.doi.org/10.1038/jid.2011.202