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Inhibition of Transcription Factor Specificity Protein 1 Alters the Gene Expression Profile of Keratinocytes Leading to Up-regulation of Kallikrein-related Peptidases and TSLP
Transcription factor specificity protein 1 (Sp1) is involved in diverse cellular functions. We recently found that Sp1 was significantly decreased in skin biopsies from patients with atopic dermatitis (AD) and had an even greater reduction in AD patients with a history of eczema herpeticum. In the c...
Autores principales: | Bin, Lianghua, Kim, Byung Eui, Hall, Clifton F, Leach, Sonia M, Leung, Donald YM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193562/ https://www.ncbi.nlm.nih.gov/pubmed/21753780 http://dx.doi.org/10.1038/jid.2011.202 |
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