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Establishment of murine basal cell carcinoma allografts – a potential model for preclinical drug testing and for molecular analysis

Dysregulated hedgehog (HH) signaling has been found in numerous cancers, suggesting that therapeutic targeting of this pathway may be useful vs. a wide range of cancers. Basal cell carcinoma (BCC) is an excellent model system for studying the influence of the HH pathway on carcinogenesis because abe...

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Detalles Bibliográficos
Autores principales: Wang, Grace Ying, So, Po-Lin, Wang, Lynn, Libove, Eileen, Wang, Joy, Epstein, Ervin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193585/
https://www.ncbi.nlm.nih.gov/pubmed/21833014
http://dx.doi.org/10.1038/jid.2011.204