Microsomal prostaglandin E synthase-1 (mPGES-1) promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis

Microsomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme that couples with cyclooxygenase-2 (COX-2) for the production of PGE(2). Although COX-2 is known to mediate the growth and progression of several human cancers including hepatocellular carcinoma (HCC), the role of mPGES-1 in hepatocarci...

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Detalles Bibliográficos
Autores principales: Lu, Dongdong, Han, Chang, Wu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193853/
https://www.ncbi.nlm.nih.gov/pubmed/21743491
http://dx.doi.org/10.1038/onc.2011.287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193853/
https://www.ncbi.nlm.nih.gov/pubmed/21743491
http://dx.doi.org/10.1038/onc.2011.287

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