Cargando…

E2F1-Dependent Oncogenic Addiction of Melanoma Cells to MDM2

One of the defining features of aggressive melanomas is their complexity. Hundreds of mutations and an ever increasing list of changes in the transcriptome and proteome distinguish normal from malignant melanocytic cells. Yet, despite this altered genetic background, a long-known attribute of melano...

Descripción completa

Detalles Bibliográficos
Autores principales: Verhaegen, Monique, Checinska, Agnieszka, Riblett, Mary Beth, Wang, Shaomeng, Soengas, María S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193861/
https://www.ncbi.nlm.nih.gov/pubmed/21743494
http://dx.doi.org/10.1038/onc.2011.277