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Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit
The ubiquitously expressed 14-3-3 proteins regulate many pathways involved in transformation. Previously, we found that 14-3-3ζ overexpression increased Akt phosphorylation in human mammary epithelial cells. Here, we investigated the clinical relevance and molecular mechanism of 14-3-3ζ overexpressi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193867/ https://www.ncbi.nlm.nih.gov/pubmed/21743495 http://dx.doi.org/10.1038/onc.2011.284 |