Correlating CpG islands, motifs, and sequence variants in human chromosome 21

BACKGROUND: CpG islands are important regions in DNA. They usually appear at the 5’ end of genes containing GC-rich dinucleotides. When DNA methylation occurs, gene regulation is affected and it sometimes leads to carcinogenesis. We propose a new detection program using a hidden-markov model alongsi...

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Detalles Bibliográficos
Autores principales: Spontaneo, Leah, Cercone, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194231/
https://www.ncbi.nlm.nih.gov/pubmed/21989037
http://dx.doi.org/10.1186/1471-2164-12-S2-S10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194231/
https://www.ncbi.nlm.nih.gov/pubmed/21989037
http://dx.doi.org/10.1186/1471-2164-12-S2-S10

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