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Correlating CpG islands, motifs, and sequence variants in human chromosome 21
BACKGROUND: CpG islands are important regions in DNA. They usually appear at the 5’ end of genes containing GC-rich dinucleotides. When DNA methylation occurs, gene regulation is affected and it sometimes leads to carcinogenesis. We propose a new detection program using a hidden-markov model alongsi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194231/ https://www.ncbi.nlm.nih.gov/pubmed/21989037 http://dx.doi.org/10.1186/1471-2164-12-S2-S10 |