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Enhancement of Polymeric Immunoglobulin Receptor Transcytosis by Biparatopic VHH

The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day the human pIgR mediates the excretion of 2 to 5 gra...

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Detalles Bibliográficos
Autores principales: Emmerson, Chris D., van der Vlist, Els J., Braam, Myrthe R., Vanlandschoot, Peter, Merchiers, Pascal, de Haard, Hans J. W., Verrips, C. Theo, van Bergen en Henegouwen, Paul M. P., Dolk, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194793/
https://www.ncbi.nlm.nih.gov/pubmed/22022593
http://dx.doi.org/10.1371/journal.pone.0026299