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Enhancement of Polymeric Immunoglobulin Receptor Transcytosis by Biparatopic VHH
The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day the human pIgR mediates the excretion of 2 to 5 gra...
Autores principales: | Emmerson, Chris D., van der Vlist, Els J., Braam, Myrthe R., Vanlandschoot, Peter, Merchiers, Pascal, de Haard, Hans J. W., Verrips, C. Theo, van Bergen en Henegouwen, Paul M. P., Dolk, Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194793/ https://www.ncbi.nlm.nih.gov/pubmed/22022593 http://dx.doi.org/10.1371/journal.pone.0026299 |
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