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Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs

Vectors based on γ-retroviruses or lentiviruses have been shown to stably express therapeutical transgenes and effectively cure different hematological diseases. Molecular follow up of the insertional repertoire of gene corrected cells in patients and preclinical animal models revealed different int...

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Detalles Bibliográficos
Autores principales: Abel, Ulrich, Deichmann, Annette, Nowrouzi, Ali, Gabriel, Richard, Bartholomae, Cynthia C., Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194800/
https://www.ncbi.nlm.nih.gov/pubmed/22022353
http://dx.doi.org/10.1371/journal.pone.0024247