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Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs
Vectors based on γ-retroviruses or lentiviruses have been shown to stably express therapeutical transgenes and effectively cure different hematological diseases. Molecular follow up of the insertional repertoire of gene corrected cells in patients and preclinical animal models revealed different int...
Autores principales: | Abel, Ulrich, Deichmann, Annette, Nowrouzi, Ali, Gabriel, Richard, Bartholomae, Cynthia C., Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194800/ https://www.ncbi.nlm.nih.gov/pubmed/22022353 http://dx.doi.org/10.1371/journal.pone.0024247 |
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