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Genome-Wide Linkage Scan of a Pedigree with Familial Hypercholesterolemia Suggests Susceptibility Loci on Chromosomes 3q25-26 and 21q22

BACKGROUND: Familial hypercholesterolemia (FH) is a heritable disorder that can increase the risk of premature coronary heart disease. Studies suggest there are substantial genetic heterogeneities for different populations. Here we tried to identify novel susceptibility loci for FH in a Chinese pedi...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Li, Xin, Zhang, Yong-Biao, Zhang, Feng, Sun, Liyuan, Lin, Jie, Wang, Duen-Mei, Wang, Lu-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194805/
https://www.ncbi.nlm.nih.gov/pubmed/22022364
http://dx.doi.org/10.1371/journal.pone.0024838